Assessment of Palm date (Phoenix dactylifera L.) on clinical manifestation of knee Osteoarthritis

Assessment of topical Palm date (Phoenix dactylifera L.) product on clinical manifestation of knee Osteoarthritis versus Diclofenac gel: A randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180126038510N1

Enrollment

Registered

2018-08-25

Start date

2018-09-23

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of Knee. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: This group will expose Topical Palm date Preparation to their involved knees three times a day at a rate of one index of the index finger for 4 weeks.Preparation wi

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Mild to moderate knee Ostoarthritis patients according to Kellegren-Lawrence (K-L) grading scale Pain at least in one knee in last 3 month ago Minimum annoying pain in last (at least ) 4 week before randomized selection according to VAS scale

Exclusion criteria

Exclusion criteria: Allergy to topical preparation of Date palm and Diclofenac gel Skin lesion on the knee Secondary Osteoarthritis as Rhuomatoid arthritis,Gout,Infectious arthritis,Metabolic arthritis,Traumatic arthritis Operative knee joint replacement Topical or systemic steroid use since 14 day before study Intraarticular steroid injection since 90 day before study Pregnancy and lactation period Alcohol and opioid addiction Radiculopathy and Neuropathy History of any kind of knee operation and trauma Utilization of other analgesic drugs since study period Nonconformity of life style according to knee health

Design outcomes

Primary

Measure	Time frame
Score of knee pain intensity. Timepoint: Measuring the Score of knee pain intensity at the beginning of the study and 14 and 28 days after starting use of Palm date ointment. Method of measurement: Visual Analogue Scale And Western Ontario and McMaster Universities Osteoarthritis questionnaire.;Score of knee stiffness intensity. Timepoint: Measuring Score of knee stiffness intensity at the beginning of the study and 14 and 28 days after starting use of Palm date ointment. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis questionnaire.	—

Measure

Time frame

Score of knee pain intensity. Timepoint: Measuring the Score of knee pain intensity at the beginning of the study and 14 and 28 days after starting use of Palm date ointment. Method of measurement: Visual Analogue Scale And Western Ontario and McMaster Universities Osteoarthritis questionnaire.;Score of knee stiffness intensity. Timepoint: Measuring Score of knee stiffness intensity at the beginning of the study and 14 and 28 days after starting use of Palm date ointment. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis questionnaire.

—

Secondary

Measure	Time frame
Daily activity Score. Timepoint: Measuring of Daily activity Score at the beginning of the study and 14 and 28 days after starting use of Palm date ointment. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Bagherzadehkarimi

Tabriz University of Medical Sciences

Bagerzadeha@tbzmed.ac.ir+98 41 3668 3374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026