chronic renal failure. end stage renal disease
Conditions
Interventions
Intervention 1: Intervention group: 2 capsules containing 1000 mg of Nigella sativa oil made by Kashan Barij Essential Oil Company were given to the research units daily for 8 weeks. Intervention 2: C
Sponsors
Sabzevar University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: The study subjects were being dialyzed with polysulfone capillary dialyzers 3 times a week for 4 h per session The study, the hemodialysis procedure and type of dialyzer were not altered Must be able to swallow capsules
Exclusion criteria
Exclusion criteria: infectious diseases especially hepatitis patients taking Nigella sativa patients taking omega-3 fatty acid supplements, L-carnitine patients taking vitamin E and/or C supplements patients taking steroidal and/or non-steroidal anti-inflammatory drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory factors, oxidative stress marker, lipid profiles. Timepoint: At the begining and the end of week 8. Method of measurement: The serum hs-CRP concentration was determined using enzyme linked immune sorbent assay, the serum malondialdehyde (MDA) concentration was assessed using commercial colorimetric kits, the serum lipids was measured auto-analyzer with Pars Azmoon kits. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAkram Kooshki
Sabzevar University of Medical Sciences
Outcome results
None listed