Anemia. Refractory anemia, unspecified
Conditions
Interventions
Intervention 1: Intervention group: 400 mg pentoxifylline pill, made in Iran, once daily for 12 weeks, with an appropriate dosage of intravenous erythropoietin for each patient diagnosed by physician
Sponsors
Urology Research Centre, Guilan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: GFR less than 15 Have been under hemodialysis for at least 3 months Performing regular hemodialysis 3 times a week Having an iron saturation of more than 30% and ferritin more than 500 Dialysis adequacy criteria: Kt/V greater than 1/2 Have an arteriovenous fistula or a pacifier for hemodialysis Hemoglobin less than 11 in at least 2 consecutive tests within a month
Exclusion criteria
Exclusion criteria: History of bleeding in a recent month History of infection leading to hospitalization in a recent month Use of theophylline and androgens Intolerance to drug use in oral form Patient dissatisfaction The patient has undergone blood transfusion or B12 administration for any reason during the last 3 months. The presence of any underlying illness that justifies anemia, including thyroid and parathyroid dysfunction, hemoglobinopathy and malnutrition, and ... Hemorrhagic retinopathy The presence of coronary artery disease in the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin level. Timepoint: At the beginning of the study (before the intervention) and 4, 8 and 12 weeks after the intervention. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamira Rahimi
Rasht University of Medical Sciences
Outcome results
None listed