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The Comparison of Vaginal Misoprostol with buccal and sublingual Misoprostol in Labor Induction in Term Pregnancy

The Comparison of Vaginal Misoprostol with buccal and sublingual Misoprostol in Labor Induction in Term Pregnancy

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180121038465N1
Enrollment
300
Registered
2018-03-17
Start date
2018-03-14
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

induction of labour.

Interventions

Intervention 1: Intervention group: Recipient of 50 µg misoprostol by buccal method up to three doses in case of no onset of labor pain. Intervention 2: Intervention group: Recipient of 50 µg misopros

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: single, bishop score=4, cephalic presentation, NST reactive, parity =2, gestational age more than 37 w, Amniotic fluid index =5

Exclusion criteria

Exclusion criteria: maternal medical diseases breech presentation fetal anomaly

Design outcomes

Secondary

MeasureTime frame
The rate of Cesarean section. Timepoint: delivery. Method of measurement: cesarean/ NVD.;Reason of cesarean. Timepoint: during delivery. Method of measurement: mecunium, FHR deceleration, No responce to induction.;Time to the active phase of labor. Timepoint: 0-6-24 hr. Method of measurement: Bishop Score.;Need for oxytocin. Timepoint: until delivery. Method of measurement: yes/no.;Number of misoprostol doses. Timepoint: until delivery. Method of measurement: 1-2-3.;Fetal complications. Timepoint: until delivery. Method of measurement: abnormal pattern of fetal heart rate, meconium, Apgar score 1 and 5 postpartum, and admission to neonatal intensive care unit.;Maternal complication. Timepoint: until delivery. Method of measurement: Fever, chills, nausea, vomiting, uterine tachysystole, uterine hyperstimulation.

Primary

MeasureTime frame
The effect of misoprostol in induction of labor. Timepoint: every 6h to 24h. Method of measurement: bishop score and time of delivery.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRazieh Akbari

Qazvin University of Medical Sciences

raziehakbari9@gmail.com+98 21 3350 4866

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026