Effect of melatonin on cortisol and sleep quality of Hemodialysis Patients

Study of the effects of short-term melatonin on salivary cortisol and sleep quality of hemodialysis patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180117038418N1

Enrollment

Registered

2018-02-11

Start date

2018-01-21

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: sleep disorder. Condition 2: chronic renal failure. Sleep disorders Chronic kidney disease, stage 5

Interventions

Intervention 1: Intervention group: 3 mg melatonin capsule made in Canada, which is consumed by participants for 2 weeks each night at 10 o'clock. Intervention 2: Control group: Chickpea flour capsule

Eligibility

Sex/Gender

All

Age

No minimum to 75 Years

Inclusion criteria

Inclusion criteria: ESRD patients undergoing hemodialysis >3 months age =5

Exclusion criteria

Exclusion criteria: serious and sever illness (e.g; malignancy, CHF, active infection) pregnancy iron deficiency anemia poor control diabet (HbA1c>7.5) sever deppresion psychotic disorders use of hypnotics continuelly use of corticosteroid

Design outcomes

Primary

Measure	Time frame
Sleep quality score in Pittsburgh questionnaire. Timepoint: Sleep quality study at the beginning of the study (before the intervention) and 2 weeks later (end of study). Method of measurement: Pittsburgh questionnaire.;Salivary Cortisol Level. Timepoint: Measurement of salivary cortisol level at the beginning of the study at night before and the next morning before the start of dialysis and 2 weeks later (end of study) in the same way. Method of measurement: Cortisol measurement kit, chemiluminescence method.	—

Measure

Time frame

Sleep quality score in Pittsburgh questionnaire. Timepoint: Sleep quality study at the beginning of the study (before the intervention) and 2 weeks later (end of study). Method of measurement: Pittsburgh questionnaire.;Salivary Cortisol Level. Timepoint: Measurement of salivary cortisol level at the beginning of the study at night before and the next morning before the start of dialysis and 2 weeks later (end of study) in the same way. Method of measurement: Cortisol measurement kit, chemiluminescence method.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Hasannia

Gorgan University of Medical Sciences

elihasania@gmail.com+98 17 3222 0563

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026