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A comparative study on the prophylactic effect of Dexmedetomidine and Paracetamol on intraoperative hemodynamic control and postoperative pain in patients undergoing laparoscopic cholecystectomy

A comparative study on the prophylactic effect of Dexmedetomidine and Paracetamol on intraoperative hemodynamic control and postoperative pain in patients undergoing laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180115038381N1
Enrollment
132
Registered
2019-02-18
Start date
2017-05-05
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Postoperative pain after Laparoscopic Cholecystectom. Condition 2: Peri-operative Hemodynamic.

Interventions

Intervention 1: The first intervention group included 66 patients undergoing laparoscopic cholecystectomy and receiving doxedemotomidine. Patients in this group receive 1 µg / Kg stat and then 0.5 µg

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients who are indicated for emergency or elective Laparoscopic Cholecystectomy. Obtaining informed consent Both genders Patients between 18 to 70 years old

Exclusion criteria

Exclusion criteria: Conversion of Laparoscopic surgery to open surgery Partial Cholecystectomy Gangrenous Gall bladder Abscess Major trauma to Bile ducts

Design outcomes

Primary

MeasureTime frame
Mean Arterial Blood Pressure. Timepoint: Immediately after Anesthesia induction, 30 minutes after surgery, 1 hour after surgery, 90 minutes after surgery. Method of measurement: Blood pressure gauge.;Pulse Rate. Timepoint: Immediately after Anesthesia induction, 30 minutes after surgery, 1 hour after surgery, 90 minutes after surgery. Method of measurement: Measured by the questioner.;Postoperative Pain. Timepoint: In Recovery Unit, 4 hour after surgery, 12 hour after surgery, 24 hour after surgery. Method of measurement: With Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTaha Hojjati Ashrafi

Arak University of Medical Sciences

taha.hojjati@arakmu.ac.ir+98 86 3313 1639

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026