effect of folic acid in depression

Effects of folic acid supplementation in patients with major depressive disorder receiving Citalopram.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180115038373N1

Enrollment

Registered

2018-10-06

Start date

2018-01-05

Completion date

Unknown

Last updated

2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder. Major depressive disorder, single episode, severe without psychotic features

Interventions

Intervention 1: Intervention group: receiving acid folic 1mg/day (Rouz Darou) and citalopram 20 mg/day. Intervention 2: Control group: citalopram 20 mg.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: depressed people, the number of beck scale should be more than 15

Exclusion criteria

Exclusion criteria: having other psychotic disorders, like psychos, bipolar disorder, drug abusers,pregnancy, and depression because of an illness

Design outcomes

Primary

Measure	Time frame
Depression severity with the results of Beck scale. Timepoint: Measureing the severity of depression at the beginning of the study, day 45, day90. Method of measurement: Beck and Hamilton scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactIslambulchilar Mina

Zanjan University of Medical Sciences

islambulchilar.mina@gmail.com+98 24 3347 3635

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026