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The effect of mouthwash containing Tabashir extract on oral ulcers in paraquat poisoning

Investigating the effect of mouthwash containing Tabashir (Saccharum Ravennae) extract on oral mucosal ulcers in case of paraquat poisoning

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180114038356N5
Enrollment
30
Registered
2024-06-11
Start date
2024-04-06
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

paraquat poisening.

Interventions

Intervention 1: Intervention group: triamcinolone paste : 3 times a day every 8 hours to the extent that the wound surface is covered. Intervention 2: Intervention group: mouthwash made from the combi

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Occurrence of oral and pharyngeal wounds in the injured

Exclusion criteria

Exclusion criteria: Symptoms of esophageal perforation Frequent nausea and vomiting in a person Chronic hypotension

Design outcomes

Primary

MeasureTime frame
Duration of recovery of oral ulcer, amount of pain, change in lesion size, duration of recovery of dysphagia, duration of recovery of difficulty in eating normal food, duration of recovery of difficulty in moving the mouth, duration of reduction of the affected areas in the mouth. Timepoint: Before intervention, 7, 14, 21, 28 days after intervention. Method of measurement: There is no valid scoring system that exclusively measures the severity of oral lesions and the extent of involvement, except for the Oral Disease Severity Score (ODSS), which also has problems and cannot easily express the degree of erosion or ulceration; As a result, the Pemphigus Oral Lesions Intensity Score (POLIS) scale can be used, it is worth mentioning that we have examined 7 of the 16 items in the POLIS scale: 1) the amount of change (decrease or increase) in the size of oral lesions during treatment 2) difficulty in eating normal food 3) examination of difficulty in eating food according to its consistency 4) difficulty in speaking 5) difficulty in swallowing 6) number of areas involved in the oral cavity 7) discomfort while opening and moving the mouth.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayyeh Karami-Mohajeri

Kerman University of Medical Sciences

somayyehkarami@gmail.com+98 34 3132 5001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026