Patients addicted to opioids treated with methadone. Mental and behavioural disorders due to use of opioids
Conditions
Interventions
Intervention 1: Intervention group: 28 patients under methadone therapy will be assigned to the treatment group to receive the extract (500 mg, twice a day for 30 days). Intervention 2: Control group:
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Opioid addiction of at least 2.3 grams per day continuously for at least one year, Age between 20-60 years old No history of medical comorbidities No history of allergies to this plant
Exclusion criteria
Exclusion criteria: History of medical comorbidities History of allergies to this plant Do not take the capsules Dissatisfaction with methadone dose reduction Intolerance to some of side effects of the extract, such as dry mouth
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Examination of opioid withdrawal symptoms and neurological complications with the questionnaires. Timepoint: Before intervention and 7, 14 and 28 days after intervention. Method of measurement: Questionnaires. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of depression, anxiety, sleep quality. Timepoint: Before intervention and 7, 14 and 28 days after intervention. Method of measurement: Questionnaires. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSomayyeh Karami-Mohajeri
Kerman University of Medical Sciences
Outcome results
None listed