constipation in adult. Constipation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria : 1-age over 20 years 2. Have at least 2 of the following criteria; - Straining during at least 25 percent of defecations - Lumpy or hard stools in at least 25 percent of defecations -Sensation of incomplete evacuation for at least 25 percent of defecations -Sensation of anorectal obstruction/blockage for at least 25 percent of defecations -Manual maneuvers to facilitate at least 25 percent of defecations -Fewer than three defecations per week 3. during the last month,Without the use of laxatives, rarely have soft stool 4. Patient satisfaction to participate in the study
Exclusion criteria
Exclusion criteria: Exclousion criterias: 1- Use medications Anti-seizures, Carbamazepine, Phenobarbital, Phenytoin, Anti-neoplastic, Calcium channel blockers: Verapamil, Diuretics: Forzamide, Anti-epileptic drugs, Anti-epileptic drugs, Anti-epileptic drugs. , 5-HT antagonists, NSAIDs: ibuprofen, opioid. 2. History of mechanical and False intestinal obstruction based on previous colonoscopy or radiography or history 3 - Metabolic and endocrine diseases such as Diabetes, Hyperthyroidism and Hypothyroidism, Hypercalcemia, Hypokalemia, Pan-Hypopyothelium, Pheochromocytoma, Porphyria 4. Neurological disease and myopathic amyloidosis, autonomic neuropathy, Chagas disease, dermatomyositis, multiple sclerosis, Parkinson's disease, systemic progressive sclerosis, spinal cord injury based on biography and history 5-Special surgical and special medical conditions such as inability to move, history of Intestine surgery, ... 6. Endoscopy and radiology report in the last 5 years on abnormalities, malignancy, IBD and hemorrhoids 7-Patients with abnormal Hgb, TFT, Ca, and ESR. 8-Patients with HTN or Diabetes 9 -Patients with Asthma and Bronchitis 10.-Patients with Renal failure 11. Pregnant and nursing women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of defecation in the week. Timepoint: Frequency of defecation in the subjects before the internvention and in the 14th day and 28th day after startinig intervention. Method of measurement: questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of straining in the defecation. Timepoint: Before the beginning of the Intervention and in the 14th day and 28th day after starting the Intervention. Method of measurement: questionnaire.;Frequency of lumpy or hard stools. Timepoint: Before the beginning of the Intervention and in the 14th day and 28th day after starting the Intervention. Method of measurement: questionnaire.;Sensation of incomplete evacuation after defecation. Timepoint: Before the beginning of the Intervention and in the 14th day and 28th day after starting the Intervention. Method of measurement: questionnaire.;Frequency of Manual maneuvers to facilitate. Timepoint: Before the beginning of the Intervention and in the 14th day and 28th day after starting the Intervention. Method of measurement: questionnaire.;Occurrence of stool. Timepoint: Before the beginning of the Intervention and in the 14th day and 28th day after starting the Intervention. Method of measurement: questionnaire.;Other related symptoms. Timepoint: Before the beginning of the Intervention and in the 14th day and 28th day after starting the Intervention. Method of measurement: questionnaire.;Side effect. Timepoint: Before the beginning of the Intervention and in the 14th day and 28th day after starting the Intervention. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Gorgan University of Medical Sciences