The Effect of Topical Ketorolac on Diabetic Macular Edema

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180114038350N2

Enrollment

Registered

2018-09-25

Start date

2018-05-20

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Macular Edema. Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema

Interventions

Intervention 1: Intervention group: Group who receive Topical Ketorolac. Intervention 2: Control group: Group who receive artificial tears.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with Diabetic Macular Edema Age more than 18 years

Exclusion criteria

Exclusion criteria: History of cataract surgery and vitrectomy history of laser therapy of Avastin injection HbA1C Instability Sensitivity to the NSAIDs (NSAIDs or Aspirine-induced Asthma) Pregnancy Severe retinopathy and active PDR Retinal disorder( VR-traction,...)

Design outcomes

Primary

Measure	Time frame
Any changes in Macular Edema. Timepoint: Before intervention and one month after treatment initiation. Method of measurement: Optical Coherence Tomography (OCT).	—

Secondary

Measure	Time frame
Any changes in visual Acuity. Timepoint: Before intervention and one month after treatment. Method of measurement: Snellen Chart.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhaled Rahmani

Sanandaj University of Medical Sciences

khaledrahmani111@muk.ac.ir+98 87 3366 4673

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026