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Efficacy of oralTranexamicAcid in melasma

Comparison of efficacy of oralTranexamicAcid with4% topical hydroquinone in the treatment of melasma.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180111038311N1
Enrollment
62
Registered
2018-04-03
Start date
2017-08-23
Completion date
Unknown
Last updated
2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melasema. Chloasma

Interventions

Intervention 1: Administration of the 250 mg Transxamic Acid Capsule Amin Pharmaceutical Company, Trancid capsule 250 milligram, is administered every 12 hours.On patients with melasma at the age of 1

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with melasma with 18- 60 years old rang.

Exclusion criteria

Exclusion criteria: Patients with coagulopathy Patients with thrombotic complications Any of thrombotic events Use of anticoagulant drugs or anti-platelet such as aspirin or Clopidogrel Pregnancy, lactation, concomitant use of contraceptives, The history of vitiligo or other pigmentation disorders, Trancexamic Acid Sensitivity History renal failure History of treatment for melasma with clarifying drugs in 3 months before the start of the study.

Design outcomes

Primary

MeasureTime frame
Pigmentation. Timepoint: MASIS record before intervention - one month and three months after intervention. Method of measurement: MASI Score.

Secondary

MeasureTime frame
Gastrointestinal complications. Timepoint: before intervention - one month and three months after intervention. Method of measurement: Ask the patients.;Hypomenorea. Timepoint: before intervention - one month and three months after intervention. Method of measurement: ASk the patients.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamin Vala

Ahvaz University of Medical Sciences

vala.s@ajums.ac.ir+98 61322229223580

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026