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Effect of oropharyngeal decontamination by topical antibiotics on the ventilator associated pneumonia

Effect of oropharyngeal decontamination by topical antibiotics on incidence of ventilator-associated pneumonia in hospitalized traumatic patients in intensive care units

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180110038298N1
Enrollment
100
Registered
2018-02-23
Start date
2018-02-04
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator associated pneumonia. Ventilator associated pneumonia

Interventions

Intervention 1: Intervention group: On the first day of intubation, oral washing perform four times a day, with normal saline solution. On the second day of intubation, collect the initial sample of t

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The age of the patient is between 18 and 65 years Perform intubation in the first 24 hours and stay at least 72 hours Clinical pulmonary infection score less than 6 at the time of arrival Oral hygiene assessment checklist score 10 or less GCS less than 9

Exclusion criteria

Exclusion criteria: damage to the mouth, jaw and face cancer and diabetes and chronic obstructive pulmonary disease immunosuppression due to certain medications or diseases history of broad-based antibiotic therapy in the past 3 months perform a cardiopulmonary resuscitation process

Design outcomes

Primary

MeasureTime frame
The incidence of ventilator-dependent pneumonia. Timepoint: At the beginning of the study, before the intervention, and daily until the end of the intervention. Method of measurement: Clinical pulmonary infection score.

Secondary

MeasureTime frame
Microorganisms grown from pharyngeal and tracheal secretion samples. Timepoint: The first day of the study before the intervention and 5. Method of measurement: Perform culturing in the laboratory by a laboratory collaborator.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMorteza Barani

Zahedan University of Medical Sciences

mimbaran@yahoo.com+98 54 3344 2482

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026