Effect of Ephedrine and Norepinephrine in treatment of hypotension in general anesthesia

Comparison of the Effectiveness of intravenous bolus Ephedrine and Norepinephrine for the reduction of Hypotension in general Anesthesia in patient with Hypertension

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180110038296N1

Enrollment

Registered

2018-01-28

Start date

2017-01-04

Completion date

Unknown

Last updated

2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension. Hypotension, unspecified

Interventions

Intervention 1: Intervention group:Ephedrine Group: After a mean arterial pressure (MAP) drop to less than 60 millimeter Hg? one milliliter of Ephedrine with a concentration of five milligrams per mi

Eligibility

Sex/Gender

All

Age

20 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age between 20 ti 75 years old History of Hypertension General anesthesia in spinal surgery Mean arterial pressure below 60 millimeter Hg during anesthesia

Exclusion criteria

Exclusion criteria: History of cardiac arrhythmia History of valvular heart disease History of cerebral vascular disease History of renal failure Use Beta blocker drugs History of diabetes

Design outcomes

Primary

Measure	Time frame
Mean Arterial Pressure. Timepoint: During Anesthesia. Method of measurement: Radial artery catheter.;Heart rate. Timepoint: During anesthesia. Method of measurement: Using a monitoring device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahar Masghati

Iran University of Medical Sciences

saharmasghati@gmail.com+98 21 6435 2326

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026