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Comparing the effect of vitamin A ointment and Liposic gel for prevention of corneal abrasion

Comparing the effect of vitamin A ointment and Liposic gel for prevention of corneal abrasion during general anesthesia in nonocular surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180107038251N4
Enrollment
50
Registered
2020-10-14
Start date
2021-02-19
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal abrasion. Injury of conjunctiva and corneal abrasion without foreign body

Interventions

Intervention 1: Intervention group1: As soon as anesthesia and blinking reflex disappears, in the first group, eye care is given with vitamin A so that the researcher first washes his hands and wears

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients older than 18 years and less than 75 years Patients undergoing non-ocular surgery with general anesthesia No obvious damage to face and eyes Lack of recent hospitalization in intensive care unit No eye damage before surgery according to the patient No eye diseases (keratitis, keratopathy, glaucoma and other eye diseases) American Society Of Anesthesiologist Physical status I and II Patients with endotracheal intubation Duration of surgery between 60-300 minutes Supine position during surgery No allergy to fluorescein No pregnancy Negative preoperative fluorescein staining No severe systemic diseases Do not use drugs that affect the production of tears in a recent month

Exclusion criteria

Exclusion criteria: Head and neck surgery Death during surgery Lack of patient cooperation and inability to answer questions related to ocular symptoms after surgery Need for invasive interventions and hospitalization in intensive care units End of surgery before 60 minutes

Design outcomes

Primary

MeasureTime frame
Corneal abrasion. Timepoint: Immediately after anesthesia, when leaving the recovery room, 24 hours after surgery. Method of measurement: Fluorescein paper and a flashlight with a cobalt blue light filter are used to assess corneal abrasion.

Secondary

MeasureTime frame
Ophthalmic discomfort. Timepoint: 24 hours after surgery. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Amini

Arak University of Medical Sciences

nazaninamini69@yahoo.com+98 86 3417 3507

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026