Osteoarthritis, effusion, knee, prolotherapy. Generalized osteoarthritis NOS
Conditions
Interventions
Intervention 1: In intervention group number 1, intra-articular injection was performed alone in patients with knee osteoarthritis. In this intervention, 3 cc saline solution 5% and 2 cc of lidocaine
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: Completing informed consent Presence of pain and other clinical symptoms of knee osteoarthritis in the last month
Exclusion criteria
Exclusion criteria: Diabetes, rheumatic diseases and collagen and vascular disease Gout and lupus, radiculopathy, nerve injury and neuropathy Brucella infection BMI> 42 History of knee replacement on the affected side, Bleeding disorder, inability to communicate and complete questionnaires History of allergy and allergic reaction to used drugs History of significant liver, kidney and cardiovascular disorders History of injections inside or around the joint in the Last 3 months Pregnant women People who have cancer People who are on the go Use of anticoagulants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Individuals with knee joint osteoarthritis without effusion accopmpanied by pain. Timepoint: In both groups before treatment and 2 weeks after the last injection. Method of measurement: The standard questionnaire of VAS, WOMAC, OKS, which is one of the most commonly used outcome measures in the treatment of knee osteoarthritis, was completed. VAS For pain levels, WOMAC is used to check the pain in everyday activities. OKS is also used to assess the amount of pain and the ability to perform various activities.;Individuals with knee joint osteoarthritis without effusion accopmpanied by limitation of motion of knee joint. Timepoint: In both groups before treatment and 2 weeks after the last injection. Method of measurement: The standard questionnaire of VAS, WOMAC, OKS, which is one of the most commonly used outcome measures in the treatment of knee osteoarthritis, was completed. VAS For pain levels, WOMAC is used to check the pain in everyday activities. OKS is also used to assess the amount of pain and the ability to perform various activities.;Individuals with knee joint osteoarthritis without effusion accopmpanied by knee joint stiffness. Timepoint: In both groups before treatment and 2 weeks after the last injection. Method of measurement: The standard questionnaire of VAS, WOMAC, OKS, which is one of the most commonly used outcome measures in the treatment of knee osteoarthritis, was completed. VAS For pain levels, WOMAC is used to check the pain in everyday activities. OKS is also used to assess the amount of pain and the ability to perform various activities. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSharareh Roshanzamir
Shiraz University of Medical Sciences
Outcome results
None listed