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The effect of dexamethasone and methylprednisolone on post endodontic pain

Comparison the effect of infiltration injection of dexamethasone and methylprednisolone on post endodontic pain in molars with necrosis pulp

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180104038222N1
Enrollment
80
Registered
2018-11-02
Start date
2018-11-06
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post treatment endodontic pain. Other specified disorders of teeth and supporting structures

Interventions

Intervention 1: Intervention group 1: Injection of 4 mg per cc dexamethasone in buccal vestibule after anesthetic injection. The drug is made in Iran and from the Alborz Pharmaceuticals Company with

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Required endodontic treatment in upper or lower molar teeth between 18 and 60 years of age Patients who are in healthy condition ASA 1 or 2 No periapical pathosis

Exclusion criteria

Exclusion criteria: Patients who have received anti-inflammatory or analgesic drugs within last 8 hours Have a periodontal abscess or acute endodontic disease or any periodontal disease They need antibiotic prophylaxis Pregnant or lactating Have mental disabilities Have systemic disease which are contraindicated with endodontic treatment Have an acute infection Sensitivity to Dexamethasone and Methyl Prednisolone

Design outcomes

Primary

MeasureTime frame
Post treatment endodontic pain intensity. Timepoint: level of pain before root canal treatment and after 6,12, 24 and 48 hours. Method of measurement: Heft-parker visual analoug scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSheyda Yeganegi Asl

Yasouj University of Medical Sciences

Mohammad.layegh@Yums.ac.ir+98 74 3322 8071

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026