Multiple sclerosis. Multiple sclerosis
Conditions
Interventions
Intervention 1: Intervention group: Patients with MS receiving 2 capsules containing 300 mg of Capparis spinosa extract once a day for 3 months. Intervention 2: Control group: Patients with MS receivi
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients with multiple sclerosis (MS) Having an EDSS score between zero and 5.5 Having stable and regular drug treatment in the last 4 weeks Consent not to use complementary medicines from 7 days before the start of the intervention until the end of the intervention Age between 18 and 60 years Consent to admission to the study
Exclusion criteria
Exclusion criteria: History of alcohol or drug addiction History of pregnancy or breastfeeding in the last 12 months Kidney and liver dysfunction Treatment with steroids during the last 2 months before the start of the study Having a neurological disease in addition to MS Having cardiovascular or infectious disease Having a history of severe respiratory or skin sensitivity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in disease symptoms based on EDSS. Timepoint: At the beginning of the study and after 3 months of treatment. Method of measurement: Checklist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in Interleukin-4 levels. Timepoint: At the beginning of the study and after 3 months of treatment. Method of measurement: Laboratory kit.;Changes in Interferon-gamma levels. Timepoint: At the beginning of the study and after 3 months of treatment. Method of measurement: Laboratory kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahid Reza Askari
Mashhad University of Medical Sciences
Outcome results
None listed