Skip to content

Comparison of the effect of two doses of filgrastim in the treatment of neutropenia

Comparative study of two doses of filgrastim (5 and 15 Microgram/ kg) on the absolute neutrophil count in children with cancer

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180103038196N8
Enrollment
60
Registered
2019-07-13
Start date
2019-02-20
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neutropenia. Neutropenia

Interventions

Intervention 1: First intervention group: Patients will receive daily 5µg/kg of G-CSF (Filgrastim brand) in addition to the antibiotic received in accordance to the protocol. Intervention 2: Second in

Sponsors

Gorgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 14 Years

Inclusion criteria

Inclusion criteria: patients with cancer associated with neutropenia Parents' informed consent for their child's participation in the study patients with absolute neutrophil count<1500 with one of the following items: Neutropenia lasts for more than 7-10 days Low blood pressure Profound neutropenia Sepsis pneumonia fungal infections

Exclusion criteria

Exclusion criteria: Patients with less than 1500 neutrophils while they have active leukemia or their leukemia is not in the remission phase.

Design outcomes

Primary

MeasureTime frame
ANC increase rate. Timepoint: Each 48 hours will be done, and when the ANC is over 1500, the medication will be discontinued. Method of measurement: Study of CBC Elements.;Number of hospitalization days. Timepoint: Hospitalize duration. Method of measurement: from patient documents.;Number of days that patient received antibiotics. Timepoint: Hospitalize duration. Method of measurement: from patient documents.;Time taken to stop the fever. Timepoint: Hospitalize duration. Method of measurement: from patient documents.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Sepide Bagheri

Gorgan University of Medical Sciences

salimia92@yahoo.com+98 17 1442 1657

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026