Comparison of the effect of two regimens of metformin and insulin on results of postpartum glucose tolerance test

Comparison of the efficacy of two treatment regimens of metformin and insulin therapy for diabetes on results of glucose tolerance test after delivery in women with gestational diabetes

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180103038196N5

Enrollment

Registered

2018-07-31

Start date

2018-05-31

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational Diabetes. Gestational diabetes mellitus

Interventions

Intervention 1: Intervention group: Group 1: Insulin therapy. Intervention 2: Intervention group: Group 2: Treatment with metformin.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Single pregnancy pregnancy Gestational age 20 to 34 weeks Diet and exercise treatment for at least a week without blood glucose control absence of risk factors for lactic acidosis and the absence of anatomical and chromosomal abnormalities fasting blood sugar greater than or equal to 126 mg / dl , HbA1C levels greater than 6.5%

Exclusion criteria

Exclusion criteria: Diagnosis of pre-pregnancy diabetes, presence of metabolic disorders in the patient Need to start treatment with insulin in oral treatment patients The lower limit of fasting glucose is 92 mg / dL and glucose levels will start for insulin patients two hours after meals, if treatment with metformin is higher than 120. Dissatisfied to cooperate in the study metabolic disorder in the patient

Design outcomes

Primary

Measure	Time frame
Control of serum glucose level in pregnant women with gestational diabetes mellitus. Timepoint: 4 days and 6 weeks after delivery. Method of measurement: Oral Glucose Tolerance Test and HbA1C Test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Moghadaseh Jahanshahi

Gorgan University of Medical Sciences

salimia92@yahoo.com+98 17 3225 1502

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026