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The effect of omega-3 and Hydroxyzine on the degree and severity of pruritus in hemodialysis patients

Comparison of omega-3 and Hydroxyzine efficacy on severity and degree of pruritus in hemodialysis dependent patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180103038196N3
Enrollment
50
Registered
2018-06-08
Start date
2018-05-14
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

end stage renal disease. Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease

Interventions

Intervention 1: Intervention group 1: Patients will be prescribed omega-3 capsules 1 g every 8 hours for 20 days (3 grams of fish oil per day). Intervention 2: Intervention group 2: In the second grou

Sponsors

Gorgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients with definite ESRD diagnosis refer to dialysis centers for hemodialysis dialysis-induced itching

Exclusion criteria

Exclusion criteria: History of itching due to skin problems before kidney failure Patients with systemic diseases like malignancy, cholestasis, hepatitis The patient with hemoglobin less than 10 K(dialyzer clearance of urea)T(dialysis time)/V( volume of distribution of urea ) index less than 1.2

Design outcomes

Primary

MeasureTime frame
The severity of itching caused by hemodialysis. Timepoint: The patients will be checked every week and they will be questioned for itching between two visits . Method of measurement: itching severity questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mahboubeh Sangbari

Gorgan University of Medical Sciences

maryarya@yahoo.com+98 44 21660

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026