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Comparison of effects of misoprostol with evening primrose on ripening of the cervix in nulliparous women

Comparison of effects of vaginal misoprostol tablet with vaginal evening primrose capsule on ripening of the cervix in nulliparous women

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180101038176N1
Enrollment
90
Registered
2018-03-03
Start date
2018-03-12
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ripening of the cervix.

Interventions

Intervention 1: The evening primrose group, 1000 mg capsule of evening primrose Vaginal, from the 40th week of gestation, is given one day per day for one week and Placed by the researcher in their ce

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 18-35 years old First pregnancy Singleton pregnancy Presentation of fetal cephalic Live fatal Gestational age 40 weeks based on the first day of the last menstruation and first trimester Medical ultrasound Natural pattern of fetal heartbeat No uterine contractions Bishop score less than 4 Healthy amniotic bag Mother's height is more than 150 cm BMI less than 30 Not having drug abuse Natural biophysical profiling test at the time of starting the study Having an ultrasound for pair grading (zero and one Grade) Estimated fetal weighing 2500-4000 gr based on manual examination of the abdomen or ultrasound Low risk pregnancy (Not suffering from known internal and surgical diseases and complications of pregnancy such as previa, abruption, preeclampsia, and the absence of known fetal problems) No vaginal examination a 24 hours before starting the study Avoid doing enema, sexual intercourse, laxative, herbal medicines including castor oil and homeopathic remedies, chemotherapy, breast stimulation and traditional methods of initiating Birth pain 24 hours before the start of study until the end

Exclusion criteria

Exclusion criteria: Any problems that require emergency action, such as not moving the fetus, mother's bleeding Get any herbal medicine during the study period Intercourse during the study possible side effects of the drug Cancellation of participation in the study at each stage

Design outcomes

Primary

MeasureTime frame
Ripening of the cervix. Timepoint: since the onset of intervention and labor. Method of measurement: Bishop's Scoreboard.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNarges Mirzade

Shahid Beheshti University of Medical Sciences

nargesmirzade@sbmu.ac.ir+98 21 8820 2512

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026