The study of the preventive effect of adding Morphin to local lidocaine2% on the pain intensity after mastoidectomy-tympanoplasty surgery

Preventive effect of adding morphine to topical lidocaine in the case group compared with normal saline increase to topical lidocaine and intravenous morphine in the control group on pain intensity after mastoidectomy-tympanoplasty

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171230038142N3

Enrollment

Registered

2018-12-04

Start date

2017-05-22

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severity of pain after mastoidectomy-tympanoplasty. Follow-up examination after surgery for other conditions

Interventions

Intervention 1: The intervention group was treated with topical lidocaine 2% and epinephrine by adding 15.0 mg / kg of morphine to one hundred milligrams. Intervention 2: Control group: One hundred mg

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 15-65 years No underlying disease or at least have controled underlying disease. Patients undergoing mastoidectomy-tympanoplasty surgery

Exclusion criteria

Exclusion criteria: No history of drug and alcohol addiction No history of seizures and mental problems Lack of kidney disease

Design outcomes

Primary

Measure	Time frame
Pain intensity. Timepoint: Measurement of pain intensity at pre-induction, after induction and during surgery was measured. Method of measurement: Using the pain scale and the patient's questioning.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhalili Gholam Reza

Esfahan University of Medical Sciences

khalili@med.mui.ac.ir+98 31 3668 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026