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Sequential Therapy versus Quadruple Therapy for Helicobacter pylori Eradication

Sequential Therapy versus Quadruple Therapy for Helicobacter pylori Eradication

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171230038142N20
Enrollment
174
Registered
2020-09-19
Start date
2020-07-22
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere

Interventions

Intervention 1: Intervention group:quadruple group: 87 patients with Helicobacter pylori infection who were indicated for treatment were selected. They then received a quadruple diet with PPI + bismut

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years and older Ulcerative peptic ulcer disease based on upper gastrointestinal endoscopy

Exclusion criteria

Exclusion criteria: Having any of the following diseases: MALT, Zollinger-Ellison syndrome, various types of gastrointestinal cancers, liver or kidney diseases, other infections that require antibiotics, immunodeficiency diseases. History of upper gastrointestinal surgery History of Helicobacter pylori eradication or history of PPI use of antibiotics or probiotics (artificial or natural) during the past 4 weeks

Design outcomes

Primary

MeasureTime frame
The incidence of complications. Timepoint: Days 15 and 30 after starting treatment. Method of measurement: Question from the patient.;Duration of treatment. Timepoint: After treatment. Method of measurement: Counting the days of receiving treatment.;Helicobacter pylori eradication rate. Timepoint: After treatment. Method of measurement: Stool test.;Patient symptoms. Timepoint: Before and after treatment. Method of measurement: SF-LDQ questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtusa Hakami Fafd

Esfahan University of Medical Sciences

a.hakamifard@med.mui.ac.ir+98 31 3668 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026