Tuberous Sclerosis. Tuberous sclerosis
Conditions
Interventions
Intervention group: 15 children of 1-18 year-old with tuberous sclerosis in the face, are included in the study. They are selected by the census method and applying a thin layer of topical timolol twi
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 18 Years
Inclusion criteria
Inclusion criteria: Definitive diagnosis of tuberous sclerosis based on established Roach and Sparagana criteria Age range 1 to 18 years Written and informed consent from parents
Exclusion criteria
Exclusion criteria: Existence of active infection or symmetrical and bilateral skin lesions on the face Timolol drug interactions with the patient's medications (if taking another drug) History of timolol allergy History of other angioedema lesions in the past year Suffering from asthma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing of skin lesions. Timepoint: Before, one, two and three months after the start of the intervention. Method of measurement: Based on Global Improvement Index and before and after face photos.;The severity of facial angiofibroma. Timepoint: Before, one, two and three months after the start of the intervention. Method of measurement: Facial angiofibromas severity index(FASI) score.;Child or parent satisfaction. Timepoint: Before, one, two and three months after the start of the intervention. Method of measurement: Visual Analogue Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Reza Ghazavi
Esfahan University of Medical Sciences
Outcome results
None listed