evaluation of efficacy of synbiotics in children with eosinophilic esophagitis

evaluation of efficacy of synbiotics in resolution of symptoms , pathologic and endoscopic findings in children with eosinophilic esophagitis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171230038142N14

Enrollment

Registered

2020-03-11

Start date

2019-10-23

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

eosinophilic esophagitis. Eosinophilic esophagitis

Interventions

Intervention 1: Intervention group: They will be treated for at least 8 weeks with omeprazole (Iranian from Abidi Pharmacy) at a dose of 1 mg / kg, daily, also under appropriate diet (given nutritiona

Eligibility

Sex/Gender

All

Age

6 Months to 15 Years

Inclusion criteria

Inclusion criteria: Patient parental consent to participate in the study Eosinophilic esophagitis is diagnosed and confirmed by endoscopy Patients age 6 months to 15 years

Exclusion criteria

Exclusion criteria: Use of other medicines that can improve the disease.

Design outcomes

Primary

Measure	Time frame
Clinical symptoms. Timepoint: Before and eight weeks after intervention. Method of measurement: Examination by a pediatrician.;Pathologic findings. Timepoint: Before and eight weeks after intervention. Method of measurement: Gastric biopsy and eosinophil count by microscope.;Endoscopic findings. Timepoint: Before and eight weeks after intervention. Method of measurement: Endoscopy in hospital by pediatric gastroenterologist.	—

Measure

Time frame

Clinical symptoms. Timepoint: Before and eight weeks after intervention. Method of measurement: Examination by a pediatrician.;Pathologic findings. Timepoint: Before and eight weeks after intervention. Method of measurement: Gastric biopsy and eosinophil count by microscope.;Endoscopic findings. Timepoint: Before and eight weeks after intervention. Method of measurement: Endoscopy in hospital by pediatric gastroenterologist.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloufar Zamani

Esfahan University of Medical Sciences

gebrahimi676@gmail.com+98 31 3668 8597

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026