effect of montelukast in athma exacerbation

The effect of oral Montelukast on lung function and clinical symptoms of asthma exacerbation in Imam Hospital`s patient

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171227038108N1

Enrollment

140

Registered

2018-01-28

Start date

2018-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma exacerbation. Moderate persistent asthma with (acute) exacerbation

Interventions

Intervention 1: Intervention group: The patients that treat with montelukast 10 milligram overnight and asthma exacerbation. Intervention 2: Control group: The patients that take placebo tablet in add

Treatment - Drugs

Placebo

Intervention group: The patients that treat with montelukast 10 milligram overnight and asthma exacerbation.

Control group: The patients that take placebo tablet in addition to approved asthma exacerbation treatment.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 18 -65 years old Known case of asthma Impersion of asthma exacerbation at time of addmision

Exclusion criteria

Exclusion criteria: Intubation at time of addmision Other cause of pulmunary disease for example pneumonia Pregnancy and lactation History of hypersensitivity to montelukast Drug history of phenytoin,rifampin,phenobarbital History of smoking more than 20 pack/years

Design outcomes

Primary

Measure	Time frame
Pulmonary function tast. Timepoint: 1,3,5 day’s of addmition. Method of measurement: spirometry,peak flowmetry.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdie Fattahi

Mazandaran University of Medical Science

fattahimahdie@gmail.com+98 11 3340 8192

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026