Cinnamon and Ginger and Metformin for the treatment of polycystic ovary syndrome

The effect of cinnamon and ginger compared with metformin on anthropometric data, on Blood Glucose, Lipid and sexual hormones in women with polycystic ovary syndrome

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171227038105N1

Enrollment

100

Registered

2018-01-30

Start date

2017-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome. Polycystic ovary syndrome

Interventions

Intervention 1: First intervention group: Ginger - capsule 500 mg - 3 times a day - 8 weeks. Intervention 2: Second intervention group: Ginger - 500 mg capsule - 3 times a day - 8 weeks. Intervention

Treatment - Other

Treatment - Drugs

Placebo

First intervention group: Ginger - capsule 500 mg - 3 times a day - 8 weeks

Second intervention group: Ginger - 500 mg capsule - 3 times a day - 8 weeks

Third intervention group: metformin - 500 mg capsule - 3 times a day - 8 weeks

Control group: Rice flour - 500 mg capsule - 3 times a day - 8 weeks

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age 40-20 years Willingness to participate in the study Polycystic ovary syndrome diagnosis by a specialist according to Rotterdam criteria

Exclusion criteria

Exclusion criteria: Diabetes mellitus Pregnancy Infertility treatment useing Blood glucose-lowering drugs or Blood glucose lowering drugs cinnamon allergy Need for OCP treatment ginger allergy useing Beta-blockers useing Contraceptives Hypersensitivity Hyperprolactinemia Thyroid problems seizure cardiovascular disease cerebrovascular disease lactation useing Insulin secretagogues

Design outcomes

Primary

Measure	Time frame
Weight. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Balance.;Waist circumference. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Tape.;Hip circumference. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Tape.;FBS. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;Insulin. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;Cholesterol. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;TG. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;HDL. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;LDL. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;LH. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;FSH. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;Testosterone. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;Dehydroepiandrosterone. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;SHBG. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.	—

Measure

Time frame

Weight. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Balance.;Waist circumference. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Tape.;Hip circumference. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Tape.;FBS. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;Insulin. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;Cholesterol. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;TG. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;HDL. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;LDL. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;LH. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;FSH. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;Testosterone. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;Dehydroepiandrosterone. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.;SHBG. Timepoint: Before the experiment, eight weeks after intervention. Method of measurement: Standard enzymatic method.

—

Secondary

Measure	Time frame
BMI. Timepoint: Before the intervention and one day after the end of the intervention. Method of measurement: weight devide into height2.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarsa Dastgheib Parsa

Shiraz University of Medical Sciences

mdastgheib@sums.ac.ir+98 71 3725 1001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026