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The study of the effect of Erythropoietin on Bone union

The study of the effect of local Erythropoietin injection on Bone union in patients with Tibiofibular fracture

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171224038039N1
Enrollment
60
Registered
2018-02-21
Start date
2018-01-20
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tibiofibular fracture. Fracture of shaft of tibia

Interventions

Intervention 1: Intervention group: 30 patients with Tibiofibular fracture that Erythropoietin injected at the fracture site. Intervention 2: Control group: 30 patients with Tibiofibular fracture that

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients with Tibiofibular fractures Patients with closed fracture type A,B Fractures caused by high energy of trauma Male gender Age between 18 to 40 years

Exclusion criteria

Exclusion criteria: Patients with multiple lower injuries, metaphyseal and isolated tibial, pathologic, comminuted, osteoporotic and open fractures Patients under treatment with Steroids, Anticoagulants, Nonsteroidal Antiinflammatory drugs, Calcium Channel Blockers and Nicotine Underlying disease (Diabetes, Cardiovascular disease, etc.)

Design outcomes

Primary

MeasureTime frame
Duration of union: The duration between of sugery and time of Bone union was based on radiography and clinical examination that is defined based on month. Timepoint: At the beginning of the study and every 4 weeks after surgery. Method of measurement: Physical examination and radiographic imaging.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAsma Salehi sangani

Zahedan University of Medical Sciences

a.salehi@zaums.ac.ir+98 51 5412 3454

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026