1. Comparing the effectiveness of intravenous promethazine and diazepam

1. Comparing the effectiveness of intravenous promethazine and diazepam in treating peripheral vertigo in patients who have referred to Emergency Unit of Baqiatullah (may Allah hasten his honorable appearance) Hospital during the time span from 2015 to 2016

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171221037984N1

Enrollment

164

Registered

2018-02-06

Start date

2015-03-21

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with peripheral vertigo. Other peripheral vertigo

Interventions

Intervention 1: Intervention group: the peripheral vertigo individuals who had referred to the emergency unit were subjected to treatment by IV promethazine for a dosage of 25mg/ml. Intervention 2: Co

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 7. The individuals, above 18 years of age, with motion sickness (peripheral vertigo) who have referred to emergency unit. The exclusion criteria are: expressing dissatisfaction to participate in the study, pregnant women, history of allergy to the drugs administered in the study, a history of taking antivertigo drugs during the past 24 hours, development of drug-induced motion sickness symptoms, existence of central vertigo and a history of traumatic brain injury. The abovementioned cases can be diagnosed in examinations and the patients’ self-report

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Vertigo Treatment. Timepoint: 365 DAYS. Method of measurement: The Effectiveness OF Promethazine And Diazepam In tThe Treatment Of Peripheral Vertigo.	—

Secondary

Measure	Time frame
The individuals who had referred to the emergency unit were asked to complete the demographic characteristic and visual analog scale (VAS) forms; in such a way that the patients were asked to give a number from 1 to 12 to the intensity of vertigo they experience. In the next stage, the patients were randomly assigned to two groups (based on random numbers table). Afterwards, the first group was given IV promethazine (25 mg/ml) and the second group received IV diazepam (5mg/ml). The patients were asked to fill in the VAS form two hours after being administered with the drugs. The drug-induced symptoms, if any, were recorded in the questionnaire form. In case that the patients do not respond to the treatment favorably, a second dosage of the same drug will be prescribed. Timepoint: 25 and 5. Method of measurement: the first group was given IV promethazine (25 mg/ml) and the second group received IV diazepam (5mg/ml). The patients were asked to fill in the VAS form two hours after being administered with the drugs. The drug-induced symptoms, if any, were recorded in the questionnaire form. In case that the patients do not respond to the treatment favorably, a second dosage of the same drug will be prescribed.	—

Measure

Time frame

The individuals who had referred to the emergency unit were asked to complete the demographic characteristic and visual analog scale (VAS) forms; in such a way that the patients were asked to give a number from 1 to 12 to the intensity of vertigo they experience. In the next stage, the patients were randomly assigned to two groups (based on random numbers table). Afterwards, the first group was given IV promethazine (25 mg/ml) and the second group received IV diazepam (5mg/ml). The patients were asked to fill in the VAS form two hours after being administered with the drugs. The drug-induced symptoms, if any, were recorded in the questionnaire form. In case that the patients do not respond to the treatment favorably, a second dosage of the same drug will be prescribed. Timepoint: 25 and 5. Method of measurement: the first group was given IV promethazine (25 mg/ml) and the second group received IV diazepam (5mg/ml). The patients were asked to fill in the VAS form two hours after being administered with the drugs. The drug-induced symptoms, if any, were recorded in the questionnaire form. In case that the patients do not respond to the treatment favorably, a second dosage of the same drug will be prescribed.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Kamran Haidari

Shahid Beheshti University of Medical Sciences

Heidari-k@sbmu.ac.ir+98 21 2661 8710

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026