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The effect of mouthwash on the prevention of ventilator-acquired pneumonia

The effect of combined mouthwash on the prevention of ventilator-acquired pneumonia in mechanically ventilated patients admitted to intensive care unit

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171221037983N5
Enrollment
124
Registered
2019-09-30
Start date
2017-04-21
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanically ventilated patients. Other specified misadventures during surgical and medical care

Interventions

Intervention 1: Intervention group: combined mouthwash of gentamycin of 2%, Clestine of 2% and vancomycin of 2% that it will rubbed for 4 times per day (every 6 hours) into patients' oral mucosa with

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: mechanically ventilated patients Age over 18 years Admitted patients in the intensive care unit

Exclusion criteria

Exclusion criteria: brain death patients Patients with GCS=3 Patients with mechanical ventilation less than 48 hours

Design outcomes

Primary

MeasureTime frame
Microorganisms isolated from culture of endotracheal tube secretions. Timepoint: microorganism isolated from positive culture of endotracheal tube secretions from the onset of mouthwash till seven days after intervention or patient's death and discharge. Method of measurement: Culture of tracheal tube secretions.;Duration of mechanical ventilation. Timepoint: The length of mechanically ventilation during hospitalization at the intensive care unit. Method of measurement: Days of Mechanical Ventilation.;Mortality in patients. Timepoint: Patient's death during hospitalization at the intensive care unit. Method of measurement: Death or survival of the patient.

Secondary

MeasureTime frame
Length of stay in hospital. Timepoint: The number of hospitalization days. Method of measurement: Number of days.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Amin Valizade Hasanlouei

Oroumia University of Medical Sciences

valizademohammadamin@gmail.com+98 44 3198 8293

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026