The effect of Nitroglycerin and Labetalol on hypertension

Comparison of nitroglycerin infusion and labetalol in acute arterial hypertension controlling in intracerebral hemorrhage patients admitted to intensive care unit

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171221037983N2

Enrollment

Registered

2018-05-02

Start date

2017-03-21

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracerebral hemorrhage. Nontraumatic intracerebral hemorrhage

Interventions

Intervention 1: Intervention group: 20 mg of Labetalol (as bolus form) in primary dose as intravenously and each 20 minutes was given as a bolus dose of 20-80 mg. Intervention 2: Control group: Nitro

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with intracerebral hemorrhage Patients with arterial hypertension Patients admitted to the intensive care unit

Exclusion criteria

Exclusion criteria: Patients with history of brain neoplasm History of cerebrovascular diseases History of cardiovascular diseases

Design outcomes

Primary

Measure	Time frame
Systolic and diastolic blood pressure. Timepoint: Every hour in the first 24 hours after intervention. Method of measurement: SAADAT ALBURZ B9 Monitoring device.	—

Secondary

Measure	Time frame
Severity of disease. Timepoint: Before and after intervention. Method of measurement: GCS score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Amin Valizade Hasanlouei

Oroumia University of Medical Sciences

valizademohammadamin@gmail.com+98 44 3346 9935

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026