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Assessment of the effect of Vit D supplementation in mechanical Ventilatory Traumatic patients

Assessment of the effect of Vit D supplementation on oxidative stress markers and weaning from mechanical Ventilatory Traumatic patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171221037983N1
Enrollment
72
Registered
2018-01-11
Start date
2017-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic patients. Post-traumatic stress disorder (PTSD)

Interventions

Intervention 1: Intervention group: 5000O IU oral Vitamin D for 6 consecutive days. Intervention 2: Intervention group: Vitamin D 300,000 units are muscle and in a single dose. Intervention 3: Contr
Treatment - Drugs
Intervention group: 5000O IU oral Vitamin D for 6 consecutive days
Intervention group: Vitamin D 300,000 units are muscle and in a single dose
Control group: Patients will not receive the any intervention.

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: All mechanical Ventilatory Traumatic patients admitted to intensive acre unit The age group 18-65 years Vit D serum level between 10-3 ng/ml Minimum length of stay 7 days in ICU

Exclusion criteria

Exclusion criteria: Patients with chronic and acute renal failure Patients under hemodialysis or peritoneal dialysis GCS<9

Design outcomes

Primary

MeasureTime frame
Oxidative Stress: determining the total antioxidant capacity and IL6 serum levels. Timepoint: Baseline-7 days after intervention. Method of measurement: ELISA Test.;SOFA (Sequential organ failure assessment score). Timepoint: Baseline-7 days after intervention. Method of measurement: checklist.

Secondary

MeasureTime frame
Body composition. Timepoint: Baseline- after 7 days from intervention. Method of measurement: body Analyzer Inbody.;Mortality. Timepoint: end of study. Method of measurement: dead or live.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Amin Valizade

Oroumia University of Medical Sciences

valizadeh.ma@umsu.ac.ir+98 44 3346 9935

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026