late-onset sepsis in very preterm infants. Bacterial sepsis of newborn, unspecified
Conditions
Interventions
Intervention 1: Intervention group: 42 preterm infants with a gestational age of less than 32 weeks and a weight of between 1,000-1,500 g and matched with clinical inclusion criteria for the study ra
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to No maximum
Inclusion criteria
Inclusion criteria: Preterm infants weighting 1000-1500 g and less than 32 weeks’ gestational age at birth Enrolled within 48 hours of birth
Exclusion criteria
Exclusion criteria: Major congenital anomalies(Esophageal atresia,Omphalocele,Imperforate anus) Major congenital heart malformations Genetic anomalies(e.g Trisomy 21 or other trisomies) Considered likely to die within 72 hours of birth Death before minimal entral feeding(10-20cc/kg/day) Parents from whom informed consent cannot be obtained Sepsis in admission(CRP>10mg/dl in 1st day of admission) Asphyxia (grade II, III) Maternal chorioamnionitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Late-onset sepsis. Timepoint: Baseline(admission), weekly and when clinical sepsis suspected. Method of measurement: Measurement of C-Reactive Protein and clinical clinical evaluation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Necrotizing enterocolitis. Timepoint: On admission, every week, when symptoms of Necrotizing enterocolitis are diagnosed. Method of measurement: Clinical evaluation based on Bell's Criteria.;Duration of primary hospitalization. Timepoint: Time of discharge. Method of measurement: Count the number of hospitalization days.;The number of days the infant takes to complete entral feeding(120mL/kg per day). Timepoint: During the study period. Method of measurement: number of days until an infant to eat 120mL / kg per day of milk. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSiamack Karimi Heydarabad
Oroumia University of Medical Sciences
Outcome results
None listed