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The Effect of Clove Extract on Pain Caused by Copamer Injection in Patients with MS.

Evaluation of the Effect of Clove Extract on Pain Intensity Caused by Copamer (Glatiramer Acetate) Injection in Patients with Multiple Sclerosis.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171216037910N3
Enrollment
70
Registered
2021-03-17
Start date
2021-04-04
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain during copamer injection in Multiple Sclerosis disease. Multiple sclerosis

Interventions

Intervention 1: Topical administration of clove extract (clove) as a topical gel made by Ahura Darou Shiraz Company with the active ingredient eugenol and containing 20% of clove oil (essential oil of

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age: 18-40 years old BMI: 19- 25 No diabetic neuropathy based on the history and diagnosis of the treating physician Full consciousness and the ability to analyze the amount of pain Absence of scars and lesions at the injection site Do not receive meperidine 4 hours and morphine 5 hours before intervention Use of Copamer(Glatiramer Acetate) injection medication in patients with MS

Exclusion criteria

Exclusion criteria: Patient's sensitivity to clove extract Coagulation problem Need subcutaneous injection of another medication in the area of copamer injection Chronic pain at the site of copamer injection

Design outcomes

Primary

MeasureTime frame
Pain score in injection site after Copamer administration. Timepoint: Immediately after injection. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Vash

Sanandaj University of Medical Sciences

samiravash68@gmail.com0988733664669

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026