Vitamin B6 in elective cesarean section

Assessment of Pyridoxine (Vitamin B6) effects on the Nausea and Vomiting Rates in Patients candidate for Elective Cesarean Section

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171216037910N1

Enrollment

140

Registered

2019-04-19

Start date

2019-05-05

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting after surgery in cesarean section with spinal anesthesia.

Interventions

Intervention 1: Intervention group:Prescribing vitamin B6 : 25 mg, 20 minutes before surgery (group 1). Intervention 2: Intervention group: Prescribing vitamin B6 : 50 mg, 20 minutes before surgery

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Fasting for 8 hours before surgery candidate for elective cesarean section Patient's full health of the digestive tract Being monogamous Filling out the consent form and willingness to participate in the study

Exclusion criteria

Exclusion criteria: Patients with diabetes Contraindications for spinal anesthesia or Conversion of spinal anesthesia into general anesthesia during surgery History of vertigo and vomiting during pregnancy Patients who have used anti-emetic drugs before surgery Get psychotropic or opioid drugs Patients with a BMI greater than 28 Patients with pre-eclampsia, eclampsia, hypertension, oesophageal hernia, gastroesophageal reflux disease

Design outcomes

Primary

Measure	Time frame
Primary outcome: nausea and vomiting. Timepoint: Nausea and vomiting are investigated during surgery and recovery time, and 2, 4, 6, 12, 18, and 24 hours after surgery. Method of measurement: The BARF method is based on the BARF ruler and according to the smileys, scoring is done. 2. Qualitative method (Likert scoring criterion).	—

Secondary

Measure	Time frame
The amount of anti-emetic drugs. Timepoint: In the first 24 hours after surgery. Method of measurement: Dosage and frequency of administration.;Intensity of pain. Timepoint: Intensity of pain is investigated during recovery time, 2, 4, 6, 12, 18, and 24 hours after surgery. Method of measurement: Pain is measured using the visual analog scale.;The length of the recovery period. Timepoint: ?In the recovery period. Method of measurement: Based on time (hours).;The length of hospitalization. Timepoint: Patient admission period. Method of measurement: Based on time (day).	—

Measure

Time frame

The amount of anti-emetic drugs. Timepoint: In the first 24 hours after surgery. Method of measurement: Dosage and frequency of administration.;Intensity of pain. Timepoint: Intensity of pain is investigated during recovery time, 2, 4, 6, 12, 18, and 24 hours after surgery. Method of measurement: Pain is measured using the visual analog scale.;The length of the recovery period. Timepoint: ?In the recovery period. Method of measurement: Based on time (hours).;The length of hospitalization. Timepoint: Patient admission period. Method of measurement: Based on time (day).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Arvin Barzanji

Sanandaj University of Medical Sciences

arvin.barzanji1988@gmail.com+98 87 3334 2561

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026