Depression. Major Depressive Disorder
Conditions
Interventions
Intervention 1: Intervention group: cinnamomum tamala 250-500 mg daily plus sertraline 50-100 mg / day. Intervention 2: Control group: Placebo 250-500 mg daily with sertraline 50-100 mg / day.
Treatment - Drugs
Intervention group: cinnamomum tamala 250-500 mg daily plus sertraline 50-100 mg / day
Control group: Placebo 250-500 mg daily with sertraline 50-100 mg / day
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: presence of Major Depressive Disorder based on DSM-5 criteria baseline Hamilton Depression Rating Scale (HAM-D) (17-item) score of at least 18 18-60 years old
Exclusion criteria
Exclusion criteria: Exclusion criteria: presence of psychosis any other diagnosis in axis I and II; receiving psychotropic medications receiving any antidepressants during past one month or ECT during past two months; hypothyroidism cardiovascular problems pregnancy or nursing women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression score in Hamilton Test. Timepoint: 2,4,6. Method of measurement: Hamilton Depression Test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects. Timepoint: 1,2,4,6,Weeks. Method of measurement: Drug side effects questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaloumeh Ghaffari
Iran University of Medical Sciences
Outcome results
None listed