Effects of Zizyphus Jujuba Fruit’s product in the Childhood Functional Constipation

Comparison of tht effects of Zizyphus Jujuba Fruit’s product and Pidrolax in the Childhood Functional Constipation which referred to Rasoul Akram Clinic: a ra ndomized clinical trial

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171213037866N1

Enrollment

110

Registered

2018-05-03

Start date

2018-04-21

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric functional constipation. Constipation

Interventions

Intervention 1: Control group: Nutritional and behavioral commands and PEG daily 0.4gr / kg. Intervention 2: Control group: Nutritional and behavioral commands and Zizyphus Jujuba Fruit’s product.

Eligibility

Sex/Gender

All

Age

2 Years to 12 Years

Inclusion criteria

Inclusion criteria: Age between 2–12 years old and presence of Functional Constipation based on ROME IV

Exclusion criteria

Exclusion criteria: Any symptom of organic constipation in the history, physical examination or para clinics (such as hypothyroidism, Hirschsprung disease, chronic intestinal pseudo-obstruction) and the presence of other chronic diseases that lead to long-term use of drugs and long-term consumption of any drug that can cause constipation.

Design outcomes

Primary

Measure	Time frame
Frequency of defecation per week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;The frequency of hard stool in a week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;Frequency of fecal incontinence per week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;The frequency of painful defecation in the week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;Frequency of drug adoption by the child per week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;The frequency of side effects in weeks. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.	—

Measure

Time frame

Frequency of defecation per week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;The frequency of hard stool in a week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;Frequency of fecal incontinence per week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;The frequency of painful defecation in the week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;Frequency of drug adoption by the child per week. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.;The frequency of side effects in weeks. Timepoint: Before intervention, 1, 2, 3, 4 weeks after starting treatment. Method of measurement: Standard questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasim Behnoud

Iran University of Medical Sciences

behnoud.n@tak.iums.ac.ir+98 21 5515 2191

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026