Migraine. Migraine
Conditions
Interventions
Intervention 1: Intervention group:Levetiracetam with a starting dose of 10 mg / kg given at a dose of 20 mg / kg in a week. In children and adults, the maximum dose is 3000 mg per day before bedtime,
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to 15 Years
Inclusion criteria
Inclusion criteria: All of children with migraine headache with or without aura, at least two attack per week or four attack per month, so that the attacks cause them to consume the analgesics or interfere with everyday activities
Exclusion criteria
Exclusion criteria: Epilepsy Complicated migraine Not having the ability to record data related to the number, duration, and severity of headaches Use of other prophylactic drugs other than Levetiracetam and Amitriptyline Severe psychiatric problems like depression and ADHD Hypersensitivity to tricyclic anti depressants drugs Taking analgesic more than 4 times a week for migraine headache
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of headache. Timepoint: Before, one month later, two months later and three months after treatment began. Method of measurement: Daily Headache Registration Form.;Headache severity. Timepoint: Before, one month later, two months later and three months after treatment began. Method of measurement: Wong-Baker FACES Pain Rating Scale.;Headache frequency. Timepoint: Before, one month later, two months later and three months after treatment began. Method of measurement: Record daily diary of headache.;Improving the quality of life. Timepoint: Before, one month later, two months later and three months after treatment began. Method of measurement: PedMIDAS quality of life checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGholamreza Jelodar
Esfahan University of Medical Sciences
Outcome results
None listed