Endometriosis. Endometriosis
Conditions
Interventions
Intervention 1: Intervention group: patients will receive 5 mg melatonin tablet once a day for 2 months. Intervention 2: Control group: patients will receive placebo once a day for 2 months.
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: The eligibility of each included patients will be confirmed by the gynecologist. Subjects eligible for the study must meet all of the following criteria at randomization: •18- 45 years of age, who had complained of endometriosis with EACPP, and Sleep disturbances based on PSQI questionnaire (score = 5). •No history of surgical or medical treatments for infertility. •Not smoking, drinking alcohol, and addiction to substance. •Lack of systemic illness diseases, such as diabetes, blood pressure, seizures
Exclusion criteria
Exclusion criteria: •continuous use of sleeping pills, anticoagulants and anticonvulsants •women treated with antidepressants •use of stimulants or hypnotics or anti-anxiety medications •recent diagnosis of mood disorders or neuropsychiatric symptoms (within 8 weeks) • pregnancy or breastfeeding •known hypersensitivity to melatonin •If the patient does not want to continue to participation •Ongoing or previous pharmacologically treated depression or bipolar disorder •Work involving nightshifts
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep quality. Timepoint: Before and 2 months after intervention. Method of measurement: PSQI-19 questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pelvic pain. Timepoint: Before and two months after the intervention. Method of measurement: VAS score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactparvaneh mirabi
Babol University of Medical Sciences
Outcome results
None listed