Endometriosis. Endometriosis
Conditions
Interventions
Intervention 1: Intervention group: melatonin 10 mg tablet (Nature Made Co., USA) is given daily one hour before bedtime for 8 weeks. Intervention 2: Control group: Placebo (Hakim Pharmaceutical Compa
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Age 18 to 45 years old Stages 2, 3 and 4 endometriosis (Laparoscopic diagnosis) Complaint of moderate to severe pelvic pain and dysmenorrhea for more than 3 consecutive months
Exclusion criteria
Exclusion criteria: Mild pain (number 1-3) Causes of pelvic pain other than endometriosis Current malignancy or history of malignancy Uterine myoma PID Ovarian cyst Pregnancy Ischemic heart disease Kidney and liver failure Regular users of antidepressants and anticonvulsants Regular users of alcohol and drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dysmenorrgea. Timepoint: Before and after the intervention. Method of measurement: Visual analogue scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Size of endometrioma. Timepoint: Before and after intervention. Method of measurement: Sonography.;Number of analgesics. Timepoint: Before and after intervention. Method of measurement: Checklist.;Chronic pelvic pain. Timepoint: Before and after the intervention. Method of measurement: B&B pain scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParvaneh Mirabi
Babol University of Medical Sciences
Outcome results
None listed