Alternative medicine in thyroid eye disease (TED)

Assessment of therapeutic effects of Curcumin & Crucina on thyroid eye disease (TED)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171207037777N1

Enrollment

Registered

2019-04-09

Start date

2018-11-22

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid eye disease. Thyrotoxicosis with diffuse goiter

Interventions

Intervention 1: Intervention group 1: Steroid plus curcumin 1 capsule/day for 2 months (Sina Curcumin 80 mg capsule, Exir Nano Sina, Mashhad, Iran). Intervention 2: Intervention group 2: Steroid plus

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Thyroid eye disease with clinical activity score (CAS) equal to 1 or more

Exclusion criteria

Exclusion criteria: No consent Poor coopration

Design outcomes

Primary

Measure	Time frame
Clinical activity of eye involvement. Timepoint: Before, 1 & 2 months after initiation of intervention. Method of measurement: Clinical evaluation.;Serologic level of IL2. Timepoint: Before and 2 months after initiation of intervention. Method of measurement: ELISA.;Serologic level of TNFa. Timepoint: Before and 2 months after initiation of intervention. Method of measurement: ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAliakbar Sabermoghaddam Ranjbar

Mashhad University of Medical Sciences

saberaa@mums.ac.ir+98 51 3845 6406

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026