Skip to content

Association the combined and separate effects of the DASH diet and vitamin D supplementation on inflammatory markers and improvement of heart condition in patients with heart failure

Association the combined and separate effects of the DASH diet and vitamin D supplementation on inflammatory markers and improvement of heart condition in patients with heart failure

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171205037760N2
Enrollment
120
Registered
2023-08-08
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HEART FAILURE. Acute on chronic diastolic (congestive) heart failure

Interventions

Intervention 1: In intervention 1, 30 patients received only vitamin D. The intake of vitamin D is once a week and its duration is for two months. The supplement is given to the patients by the resear

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 65 Years

Inclusion criteria

Inclusion criteria: Willingness to cooperate with the plan 40 to 65 years old Patients with stage 1 of heart failure. In other words, patients with an %EF between 40 and 50 are included in the study. The ability to consume food properly (in other words, those patients will be selected who have the ability to consume vegetables and fruits, for example, have teeth suitable for chewing, are not hospitalized, have the ability and ability to prepare food, and or someone prepares it for them) Vitamin D levels less than 30 ng/ml

Exclusion criteria

Exclusion criteria: Pregnancy, breastfeeding, hospitalization and Malignancy Use of nutritional supplements in the last 3 months Following a special diet• Chronic kidney disease Consumption of vitamin D supplements in the last three months. Patients who do not have normal levels of creatine and urea People with moderate and severe %EF. In other words, people whose %EF is less than 40

Design outcomes

Primary

MeasureTime frame
HsCRP: One of the heart risk markers used to help determine a person's risk. It will be measured using immunoturbidometry. Timepoint: At the beginning of the study and two months after the intervention. Method of measurement: laboratory measurements, It is measured by immunoturbidometry.;ESR: erythrocyte sedimentation rate (ESR); It is an indirect measure of the degree of inflammation in the body. This test measures the sedimentation rate of red blood cells in a blood sample placed in a long, narrow, vertical tube. Timepoint: At the beginning of the study and two months after the intervention. Method of measurement: A long, narrow and vertical pipe is used for measuring. The result of the ESR test is recorded in millimeters and the duration of red blood cell sedimentation is considered. The normal level of this test is 0-29 for women and 0-22 for men.;Assessment of malnutrition:Check possible malnutrition in patients during treatment. Timepoint: At the beginning of the study and two months after the intervention. Method of measurement: It is measured through Mini nutritional assessment questionnaire .;What is blood pressure: Normal blood pressure is a vital function of the body. Blood pressure is the force that propels blood through our circulatory system, bringing oxygen or nutrients to tissues and organs through arteries. Timepoint: At the beginning of the study and two months after the intervention. Method of measurement: blood pressure monitor.;Blood fat test or lipid profile is a combination of tests that are considered to check the risks of coronary heart disease and include markers (LDL, HDL, TRIGLYCERIDE, TOTAL CHOLESTEROL) or as a preventive measure to check risks related to factors such as: Eating habits, diet, stress, exercise and lifestyle are done. Timepoint: At the beginning of the study and two months after the intervention. Method of measurement: through laboratory kits for measuring LDL, HDL, THREE TRIGLYCERIDE, TOTAL CHOLESTEROL.;Glucose reaches th

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasomeh Sadeghi

Esfahan University of Medical Sciences

sadeghimasoumeh@gmail.com+98 31 3668 0048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026