Evaluation of the improvement effects of Vitamin E on liver indexs in pationts with acute hepatitis A

Comparison and examination of the effect of vitamin E on the improvement of hepatic indexes in patients with acute hepatitis A

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171205037752N1

Enrollment

200

Registered

2018-02-01

Start date

2016-10-01

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatitis A acute. Acute hepatitis A

Interventions

Intervention 1: Intervention group: Vitamin E pearls (Alpha-Tocopherol) with chemical formula as of C29H50O2 , 400 mg per day for six months. Intervention 2: Control group: Not receiving any treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Having Coagulopathy (<PT INR) Encephalopathy intolerance po Anti HAV positive

Exclusion criteria

Exclusion criteria: HAV positive for up to 6 months Having a abdominal pain Change the color of the urine Change the stool color jaundice Taking any medication

Design outcomes

Primary

Measure	Time frame
Measurement of liver enzyme alanine aminotransferase. Timepoint: Measuring liver enzyme including Alanine aminotransferase before the intervention and two weeks, one, two, three, four and six months after prescribing vitamin E. Method of measurement: In the laboratory by an auto-analyzer.;Measuring the aspartate aminotransferase Liver Enzyme. Timepoint: Measuring liver enzyme including aspartate aminitransferase before the intervention and two weeks, one, two, three, four and six months after prescribing vitamin E. Method of measurement: In the laboratory by an auto-analyzer.	—

Measure

Time frame

Measurement of liver enzyme alanine aminotransferase. Timepoint: Measuring liver enzyme including Alanine aminotransferase before the intervention and two weeks, one, two, three, four and six months after prescribing vitamin E. Method of measurement: In the laboratory by an auto-analyzer.;Measuring the aspartate aminotransferase Liver Enzyme. Timepoint: Measuring liver enzyme including aspartate aminitransferase before the intervention and two weeks, one, two, three, four and six months after prescribing vitamin E. Method of measurement: In the laboratory by an auto-analyzer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe Bahmadisani

Zabol University of Medical Sciences

sanipharmacy@gmail.com+98 54 3223 2183

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026