Drug abuse. Drug abuse counseling and surveillance
Conditions
Interventions
Intervention 1: Intervention group: Participants will receive oxytocin nasal spray, 10IU/spray, twice a day until 28 days. (One dose in each nostril (40IU daily)). Intervention 2: Control group: One t
Treatment - Drugs
Placebo
Intervention group: Participants will receive oxytocin nasal spray, 10IU/spray, twice a day until 28 days. (One dose in each nostril (40IU daily))
Control group: One time 40 IU intranasal saline
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 18-65 years old Male Methamphetamine dependency as assessed by the substance abuse section of the Structured Clinical Interview of DSM-IV Being at the Matrix Model of treatment. Seeking treatment for methamphetamine use Patients willing to participate in the intervention
Exclusion criteria
Exclusion criteria: Suicide attempts within the past 12 months; suicidal ideas or psychotic symptoms in the past 6 months determined by a study team physician Current opioid, alcohol or sedative physical dependence or cocaine dependence Major cardiovascular disorder Abnormal liver function Having severe psychotic disorders Metabolic diseases such as diabetes Neurological diseases Positive urine tests indicating abuse of any substance or stimulant Unwillingness to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measure of desire for methamphetamine. Timepoint: Complete questionnaire weekly. Method of measurement: CCQ-Brief Questionnaire.;Depression beck score. Timepoint: Complete questionnaire weekly. Method of measurement: Questionnaire.;Anxiety beck score. Timepoint: Complete questionnaire weekly. Method of measurement: Questionnaire.;ACTH level in the blood plasma. Timepoint: Before, middle and end of study. Method of measurement: Blood screening.;Cortisol level in the blood plasma. Timepoint: Before, middle and end of study. Method of measurement: Blood screening. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbbas Azadbakht
Kashan University of Medical Sciences
Outcome results
None listed