Comparison of stress system in patients with multiple sclerosis before and after TSST intervention

Comparison of the stress response system before and after the trait social stress test (TSST) in multiple sclerosis patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171128037666N2

Enrollment

Registered

2020-04-05

Start date

2020-05-12

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

the social stress test (TSST) use to induce stress. The period of induced stress lasts approximately 10 minutes and is divided into 5-minute components. Participants will talk about their job during t

Eligibility

Sex/Gender

Male

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Definitive diagnosis of MS The duration of illness ranged from 6 months to 5 years The age range is 20-50 years No smoking during the last day

Exclusion criteria

Exclusion criteria: Having systemic diseases such as DM, HTN, cardiovascular disease, autoimmune diseases

Design outcomes

Primary

Measure	Time frame
Salivary cortisol level. Timepoint: Before and immediately after intervention. Method of measurement: ELISA kit.;Heart rate variation features. Timepoint: Before and immediately after intervention. Method of measurement: signal processing of ECG.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBoshra Hatef

Bagheiat-allah University of Medical Sciences

boshrahatef@bmsu.ac.ir+98 71 3225 3495

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026