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Compare the clinical efficacy of oral gabapentin and naproxen on the severity of bone and joint pain in brucellosis patients

Compare the clinical efficacy of oral gabapentin and naproxen on the severity of bone and joint pain in brucellosis patients admitted in Imam Hossein hospitals of Shahroud on 2016-2017

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171124037609N1
Enrollment
86
Registered
2018-02-05
Start date
2017-12-22
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brucellosis. Brucellosis, unspecified

Interventions

Intervention 1: Intervention group: 100 mg gabapentin tablets twice daily (200 mg daily). Intervention 2: Control group: 250 mg naproxen tablets twice daily (500 mg daily).

Sponsors

Shahroud University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Definitive diagnosis of brucellosis There is no history of systemic disease (such as diabetes or thyroid disease), vascular diseases, coagulation problems (eg hemophilia), history of gastrointestinal bleeding and structural disorders (scoliosis and spondylolisthesis, etc.) No neurological symptoms such as SLR and Cross-SLR, decreased tendin reflexes and decreased sensation in examination Age range 15 to 65 years Complaint of severe and Fairly intense bone and joint pain Desire and satisfaction to enter the study

Exclusion criteria

Exclusion criteria: Corticosteroid injections in the lumbar region or other areas of the body within 3 months before and during the study Dissatisfaction to continue treatment Those who use drugs A history of back pain or repetitive back pain is more than 4 times a year Taking multiple medications for other illnesses (such as hypnotics, anti-leptic, relaxants) Severe hypersensitivity to any of the two drugs, gabapentin and naproxen Dissatisfaction with cooperation and participation in the project

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: On the third, fifth and seventh day after the intervention. Method of measurement: Visual Analog Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnaz Rivjam

Shahroud University of Medical Sciences

Farnaz_r457@yahoo.com+98 21 7792 6610

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026