The effect of autologous platelet-rich plasma on spinal arthrodesis

Comparing the effectiveness of autologous PRP in postrolateral arthrodesis of lumbar spine surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20171124037606N4

Enrollment

Registered

2023-05-08

Start date

2021-10-01

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postrolateral arthrodesis after lumbar spine fixation. Pseudarthrosis after fusion or arthrodesis

Interventions

Intervention 1: Intervention group: On the day of surgery, 26 cc of venous blood was taken from the patient under sterile conditions and placed in 3 special tubes for the preparation of platelet-rich

Eligibility

Sex/Gender

All

Age

16 Years to 69 Years

Inclusion criteria

Inclusion criteria: Patients with lumbar spine fracture Patients with lumbar canal stenosis Patients with lumbar spondylolisthesis

Exclusion criteria

Exclusion criteria: Patients with a history of spine surgery Patients suspected of local infection of the spine Patients with canal stenosis or fractures of cervical and thoracic vertebrae Patients with malignancy Patients treated with immunosuppressive drugs Patients with platelet disorders Patients with severe osteoporosis

Design outcomes

Primary

Measure	Time frame
Arthrodesis rate based on Hounsfield index in CT scan images. Timepoint: Evaluation of posterolateral arthrodesis in the third, sixth and twelfth months after surgery. Method of measurement: Helical 16-slice CT scan machine.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Tabibkhooei

Iran University of Medical Sciences

tabibkhooei.a@iums.ac.ir+98 21 6435 2228

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026