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Investigation the effect of herbal supplement on lead concentration

Investigation the effect of Silymarin on reducing lead blood concentration and oxidative stress biomarkers in opioid addicts.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20171122037584N1
Enrollment
60
Registered
2018-01-07
Start date
2018-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lead poisoning. Abnormal lead level in blood

Interventions

Intervention 1: Intervention group: In this study, the intervention group included the active ingredient of silymarin in the form of a Livergol produced by Gol-Daru Company receives 420 mg daily (thre
Treatment - Drugs
Placebo
Intervention group: In this study, the intervention group included the active ingredient of silymarin in the form of a Livergol produced by Gol-Daru Company receives 420 mg daily (three times every 14
Control group: A group that receives a pill similar to Livergel as a placebo.

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 18-60 years old blood lead level>10mcg/dl opium abuser

Exclusion criteria

Exclusion criteria: Age under 18 years Get other types of other antioxidants Gastrointestinal diseases, especially absorption disorders, which can affect the effective absorption of the drug History of heart, kidney, and liver disease

Design outcomes

Primary

MeasureTime frame
Blood lead level. Timepoint: Blood lead level measurement before drug interventions and And three months after use of the medication. Method of measurement: Atomic absorption.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojdeh Mohammadi

Hamedan University of Medical Sciences

m.mohanmmadi@umsha.ac.ir+98 912 610 0687

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026