Antibiotic Associated Diarrhea.
Conditions
Interventions
Intervention 1: Intervention group: Synbiotic powder (Protexin Restore), Starting 24 hours after starting Antibiotic therapy until 7 days after finishing Antibiotic therapy, One sachet daily, produced
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Months to 14 Years
Inclusion criteria
Inclusion criteria: Children with 2 months to 14 years age Children who are admitted in Imam Hosein Hospital in Isfahan City Children who are candidate for Antibiotic therapies due to infections for equal and more than 5 days Parent's willingness to participating in this study
Exclusion criteria
Exclusion criteria: Acute or chronic diarrhea before starting Antibiotic Having Antibiotic therapy during last 2 months Having prophylactic Antibiotic treatment Having Clostridium Difficile Associated Diarrhea during last 3 months Having underlying gastrointestinal disease Having central vein catheterization Having history of using probiotics during last 7 days Having immune deficiency Having underlying cardiovascular disease Having sever malnutrition or sever illness Having long term use of medications with gastrointestinal effects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of defecation. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents.;Stool Consistency. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Bristol Stool Scale questionnaire.;Incidence of diarrhea. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents.;Diarrhea duration. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of constipation. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents.;Presence of blood in stool. Timepoint: Every 3 days after starting Antibiotic treatment to 21 days after finishing Antibiotic treatment. Method of measurement: Interview with parents. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMozhgan Goli
Esfahan University of Medical Sciences
Outcome results
None listed